Far be it from me –

How to take the news that depression has not been shown to be caused by a chemical imbalance

on July 25, 2022

Joanna Moncrieff

Summary TL;DR

For decades people have been told that depression is caused by a serotonin deficiency. This was the rationale behind the introduction of the SSRI (Selective Serotonin Reuptake Inhibitor) antidepressants in the 1990s, which were thought to work by boosting low levels of serotonin. Our research shows no evidence of low serotonin in depression, which suggests that antidepressants do not work in the way they were originally thought to work.

There are other explanations for how antidepressants affect people, and why they can be helpful that are not to do with reversing underlying brain abnormalities and have different implications. Drugs like antidepressants change normal brain chemistry and this affects people’s moods and behaviour. SSRI’s blunt both negative and positive emotions, for example, and this may provide relief for people who are acutely distressed or unhappy. Antidepressants also act through inducing hope and optimism (the placebo effect). In the long-term…

View original post 2,957 more words

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

This site uses Akismet to reduce spam. Learn how your comment data is processed.

Maggie Harris

Guyana Prize for Literature and Commonwealth Prizewinning Author & Poet

The Life of Ryan"

Welcome to The Life of Ryan

The Isle Of Thanet News

News for Ramsgate, Margate, Broadstairs and villages.

Dave's Deliberations

David Matthew chews over some [mostly Christian] issues

Alternative Psychiatric Narratives

16-17 May 2014, Birkbeck, University of London

Through my Eyes

What's it all about!

Black Isle Media

We Provide The Facts, You Make The Decisions

Policy Press Blog

Publishing with a purpose

Alan's Blog

For what it's worth.....

Dr Goat's Blog

Putting hoof to keyboard to bring you views from the farmyard on public health, public mental health and related issues. And goats. These views are my own, and do not represent those of any organisations or endorse any political perspective - but whatever I'm eating may have been stolen.

Social Anxiety Revealed

the blog of the book

the free psychotherapy network

free psychotherapy for people on low incomes and benefits

Miriam Drori, Author

writer, editor, public speaker


Campaigning to protect the 2004 Hunting Act

more follows

Because politics isn't just something that happens in the Palace of Westminster

%d bloggers like this: